Insurance does not cover compounded GLP-1s, and many plans exclude brand-name GLP-1s for weight management, so most telehealth patients pay cash. This page ranks the cash routes: compounded tirzepatide and semaglutide by verified 12-month all-in total, then the manufacturers' direct self-pay prices for the FDA-approved products. A patient who does have coverage for Zepbound or Wegovy should stop reading here and use it; a copay beats every price below.
Compounded tirzepatide, cash-pay, ranked by 12-month all-in total
- Trimi — 12-month total $1,500 on the 12-month plan ($125 per month averaged); first month $125; no membership; same price at every dose; pharmacy named: VialsRx, GreenwichRx; verified, checked August 25, 2026; flags: shipping terms unknown, consultation terms unknown.
- Amble — 12-month total $1,620 on the 6-month plan ($135 per month averaged); month-to-month $179 at maintenance doses; first month $135; no membership; same price at every dose; reported, checked August 25, 2026; flags: consultation terms unknown, assumes renewal at the same 6-month rate.
- NexLife — 12-month total $1,668 on the 12-month plan ($139 per month averaged); month-to-month $169 at maintenance doses; first month $139; no membership; same price at every dose; pharmacy named: Absolute (AbsoluteRx), Hallandale Pharmacy, Red Rock Pharmacy; verified, checked August 25, 2026.
- Telos RX — 12-month total $1,668 on the 12-month plan ($139 per month averaged); first month $139; no membership; higher-dose price not published; verified, checked August 25, 2026; flags: shipping terms unknown, consultation terms unknown, maintenance-dose price not published; assumes the starting-dose price holds.
- BMI MD — 12-month total $1,668 on the 12-month plan ($139 per month averaged); month-to-month $179 at maintenance doses; first month $139; no membership; same price at every dose; reported, checked August 19, 2026.
- CoreAge Rx — 12-month total $1,788 on the 12-month plan ($149 per month averaged); first month $149; membership terms unconfirmed; same price at every dose; verified, checked August 25, 2026; flags: membership fee amount unknown, shipping terms unknown, consultation terms unknown.
- Sunlight — 12-month total $1,884 on the month-to-month plan ($157 per month averaged); month-to-month $157 at maintenance doses; no membership; higher-dose price not published; verified, checked August 25, 2026; flags: shipping terms unknown, consultation terms unknown, maintenance-dose price not published; assumes the starting-dose price holds.
- Fifty 410 — 12-month total $2,046 on the 3-month plan ($170.50 per month averaged); month-to-month $299 at maintenance doses; first month $133; no membership; price rises with dose; pharmacy named: ProRx, BPI / The Pharmacy Hub; reported, checked August 25, 2026; flags: introductory price for the first 3 months, 3 + 9 titration model, assumes renewal at the same 3-month rate.
- HealthRX — 12-month total $2,148 on the 12-month plan ($179 per month averaged); first month $179; no membership; higher-dose price not published; verified, checked August 25, 2026; flags: shipping terms unknown, consultation terms unknown.
- Ozari Health — 12-month total $2,166 on the 3-month plan ($180.50 per month averaged); month-to-month $235 at maintenance doses; first month $125; no membership; higher-dose price not published; pharmacy named: Hallandale Pharmacy, VialsRx; verified, checked August 25, 2026; flags: consultation terms unknown, introductory price for the first 3 months, assumes renewal at the same 3-month rate.
- Fella Health — 12-month total $2,388 on the 12-month plan ($199 per month averaged); first month $199; no membership; higher-dose price not published; verified, checked August 25, 2026; flags: maintenance-dose price not published; assumes the starting-dose price holds.
- Curex — 12-month total $2,388 on the month-to-month plan ($199 per month averaged); month-to-month $199 at maintenance doses; no membership; higher-dose price not published; verified, checked August 25, 2026; flags: maintenance-dose price not published; assumes the starting-dose price holds.
Compounded semaglutide, cash-pay, ranked
- Sunlight — 12-month total $1,056 on the month-to-month plan ($88 per month averaged); month-to-month $88 at maintenance doses; no membership; higher-dose price not published; verified, checked August 25, 2026; flags: shipping terms unknown, consultation terms unknown, maintenance-dose price not published; assumes the starting-dose price holds.
- Trimi — 12-month total $1,188 on the 12-month plan ($99 per month averaged); first month $99; no membership; same price at every dose; pharmacy named: VialsRx, GreenwichRx; verified, checked August 25, 2026; flags: shipping terms unknown, consultation terms unknown.
- NexLife — 12-month total $1,428 on the 12-month plan ($119 per month averaged); month-to-month $139 at maintenance doses; first month $119; no membership; same price at every dose; pharmacy named: Absolute (AbsoluteRx), Hallandale Pharmacy, Red Rock Pharmacy; verified, checked August 25, 2026.
- Ozari Health — 12-month total $1,563 on the 3-month plan ($130.25 per month averaged); month-to-month $175 at maintenance doses; first month $86; no membership; higher-dose price not published; pharmacy named: Hallandale Pharmacy, VialsRx; verified, checked August 25, 2026; flags: consultation terms unknown, introductory price for the first 3 months, assumes renewal at the same 3-month rate.
- Orderly Meds — 12-month total $1,788 on the month-to-month plan ($149 per month averaged); month-to-month $149 at maintenance doses; no membership; same price at every dose; pharmacy named: PerfectRx / PerfectionRx, ProRx, Casa; verified, checked August 25, 2026.
- Mochi Health — 12-month total $2,057 on the month-to-month plan ($171.42 per month averaged); month-to-month $178 at maintenance doses; first month $99; membership $79/mo; same price at every dose; verified, checked August 25, 2026; flags: introductory price for the first 1 month.
- Ivím Health — 12-month total $2,100 on the 6-month plan ($175 per month averaged); first month $175; membership $75/mo; higher-dose price not published; verified, checked August 25, 2026; flags: assumes renewal at the same 6-month rate.
- Henry Meds — 12-month total $2,364 on the 12-month plan ($197 per month averaged); month-to-month $297 at maintenance doses; first month $197; no membership; same price at every dose; verified, checked August 25, 2026.
- Fifty 410 — 12-month total $2,388 on the month-to-month plan ($199 per month averaged); month-to-month $199 at maintenance doses; no membership; price rises with dose; pharmacy named: ProRx, BPI / The Pharmacy Hub; verified, checked August 25, 2026.
- Noom Med — 12-month total $2,868 on the 3-month plan ($239 per month averaged); first month $129; no membership; same price at every dose; pharmacy named: Tailor Made Compounding; verified, checked August 25, 2026; flags: introductory price for the first 1 month, assumes renewal at the same 3-month rate.
- Zappy Health — 12-month total $2,988 on the month-to-month plan ($249 per month averaged); month-to-month $249 at maintenance doses; no membership; same price at every dose; pharmacy named: The Pharmacy Hub; verified, checked August 25, 2026.
- Remedy Meds — 12-month total $3,468 on the month-to-month plan ($289 per month averaged); month-to-month $299 at maintenance doses; first month $179; no membership; same price at every dose; verified, checked August 25, 2026; flags: introductory price for the first 1 month.
Brand-name self-pay benchmarks (manufacturer direct channels)
- LillyDirect (Zepbound vials) — 12-month total $4,938 on the month-to-month plan ($411.50 per month averaged); month-to-month $449 at maintenance doses; no membership; price rises with dose; pharmacy named: Lilly-contracted mail-order pharmacy; verified, checked August 25, 2026; flags: consultation fee not modeled, 3 + 9 titration model, offer conditions: Self Pay Journey: refill within the required window; $499/$699 regular prices otherwise, offer terms stated through December 31, 2026.
- NovoCare Pharmacy (Wegovy) — 12-month total $4,038 on the month-to-month plan ($336.50 per month averaged); month-to-month $349 at maintenance doses; first month $199; no membership; price rises with dose; pharmacy named: Novo Nordisk-contracted mail-order pharmacy; verified, checked August 25, 2026; flags: consultation fee not modeled, introductory price for the first 1 month, offer conditions: new-patient initial-fill offer; eligibility rules apply.
How this page is built
Every line is generated from the pricing database at build time, so it changes when a price does. Statuses and dates come from the provider's own pages (verified) or a dated third-party source (reported); flags name every assumption. The methodology explains the totals and the price history logs every change.
Frequently asked questions
What is the cheapest GLP-1 without insurance?
Compounded semaglutide at verified prices from $88 to $139 per month, then compounded tirzepatide from $125 to $169 per month at flat-rate providers; brand-name Zepbound vials through Lilly start at $299 and Wegovy pens through NovoCare at $199 for initial fills then $349.
Can I get Zepbound without insurance?
Yes, through LillyDirect at $299 (2.5 mg), $399 (5 mg) and $449 (7.5 to 15 mg) under Lilly's Self Pay Journey terms, plus a prescription from any clinician or a telehealth service.
Is compounded cheaper than brand for a cash patient?
At maintenance doses, by roughly $280 to $310 per month against Zepbound vials; the difference buys FDA approval, a fixed-dose pen and settled legal status. The brand-versus-compounded guide sets out the trade.