Semaglutide first, because it is cheaper
Every provider in our database that offers both molecules prices compounded semaglutide below compounded tirzepatide, usually by $20 to $40 per month. Semaglutide's active ingredient costs pharmacies less and its labeled doses are smaller. So the cheapest GLP-1 plan online is, at every provider, the semaglutide plan, and this page ranks semaglutide plans first.
That does not make it the right choice for everyone. Tirzepatide produced about 47% more weight loss in the only head-to-head trial (SURMOUNT-5); semaglutide has the completed cardiovascular outcome trial (SELECT) and an FDA indication to show for it. A patient choosing on price alone should know what the price buys. The tirzepatide ranking covers the other molecule with the same method.
The cheapest semaglutide plan in the database
The lowest verified semaglutide totals are Sunlight's advertised $88 per month (assuming it holds at every dose, which the site does not state) and Trimi's $99 per month annual prepay; the lowest with no flags is NexLife's 12-month plan at $119 per month, all-inclusive and flat across doses, or $1,428 for the year; month-to-month it is $139. The lowest tirzepatide price is the same provider's 12-month plan at $139, or $1,668. Other providers that advertise semaglutide for less than $100 in the first month — several exist — do so on a starting-dose price with a separate membership, and we have not yet verified a maintenance-dose true monthly cost under $100 anywhere. When we do, it will appear here, because the ranking is computed, not chosen.
What to check before you buy the cheapest plan
- The price at your maintenance dose. If the provider's price depends on dose, ask for the 2.4 mg (semaglutide) or 15 mg (tirzepatide) price and add the membership.
- The term. The lowest rates usually require a 6- or 12-month plan. Know what you pay if you stop early.
- Cancellation. Notice periods and refund rules differ; our cancellation comparison has the details.
- The pharmacy. Confirm it is licensed in your state; our 503A vs 503B guide explains what to look for.
The ranked list below is computed from the database and ordered by 12-month all-in cost for semaglutide. Providers that offer semaglutide but whose prices are not yet verified follow it.
1rank
Patients comparing mid-to-upper market flat prices
Sunlight charges $88 per month on a month-to-month plan for compounded semaglutide (injection). That price includes the medication, clinical care and shipping; there is no separate membership fee. On our all-in basis, the lowest true monthly cost is $88 and the lowest 12-month total is $1,056 (month-to-month plan). Prices last checked August 25, 2026; status: verified.
12‑mo all‑in $1,056true monthly $88advertised $88verified · August 25, 2026
2rank
Patients able to prepay a year who have confirmed the refund terms
Trimi charges $99 per month on a 12-month plan for compounded semaglutide (injection). That price includes the medication, clinical care and shipping; there is no separate membership fee. On our all-in basis, the lowest true monthly cost is $99 and the lowest 12-month total is $1,188 (12-month plan). Prices last checked August 25, 2026; status: verified.
12‑mo all‑in $1,188true monthly $99advertised $99verified · August 25, 2026
3rank
People who want to know the exact all-in monthly cost before they start and who expect to titrate to a higher dose, where dose-based pricing would otherwise raise the bill
NexLife charges $139 per month on a month-to-month plan, $132 per month on a 3-month plan, $125 per month on a 6-month plan, and $119 per month on a 12-month plan for compounded semaglutide (injection). That price includes the medication, clinical care and shipping; there is no separate membership fee. On our all-in basis, the lowest true monthly cost is $119 and the lowest 12-month total is $1,428 (12-month plan). Prices last checked August 25, 2026; status: verified.
12‑mo all‑in $1,428true monthly $119advertised $119verified · August 25, 2026
4rank
Patients comparing starter offers who will confirm the continuing price before enrolling
Ozari Health charges $175 per month on a month-to-month plan, and $145 per month on a 3-month plan for compounded semaglutide (injection). The first 3 months are an introductory $86 per month before the recurring price applies. That price includes the medication, clinical care and shipping; there is no separate membership fee. On our all-in basis, the lowest true monthly cost is $145 and the lowest 12-month total is $1,563 (3-month plan). Prices last checked August 25, 2026; status: verified.
12‑mo all‑in $1,563true monthly $130.25advertised $86verified · August 25, 2026
5rank
Patients comparing all-in compounded plans who want oral and injectable options from one provider
Orderly Meds charges $149 per month on a month-to-month plan for compounded semaglutide (injection). That price includes the medication, clinical care and shipping; there is no separate membership fee. On our all-in basis, the lowest true monthly cost is $149 and the lowest 12-month total is $1,788 (month-to-month plan). Prices last checked August 25, 2026; status: verified.
12‑mo all‑in $1,788true monthly $149advertised $149verified · August 25, 2026
6rank
Patients who value frequent clinician contact and dietitian support and who expect to stay on lower doses, where Mochi's starting price is most competitive
Mochi Health charges $99 per month on a month-to-month plan for compounded semaglutide (injection). The first 1 month is an introductory $60 per month before the recurring price applies. A membership is billed on top of the medication: $39 for the first month, then $79 per month. On our all-in basis, the lowest true monthly cost is $178 and the lowest 12-month total is $2,057 (month-to-month plan). Prices last checked August 25, 2026; status: verified.
12‑mo all‑in $2,057true monthly $171.42advertised $60verified · August 25, 2026
7rank
Patients who want coaching and app tracking bundled with a moderately priced compounded tirzepatide plan
Ivím Health charges $124.75 per month on a 4-month plan, and $100 per month on a 6-month plan for compounded semaglutide (injection). A $75 monthly membership is billed on top of the medication. On our all-in basis, the lowest true monthly cost is $175 and the lowest 12-month total is $2,100 (6-month plan). Prices last checked August 25, 2026; status: verified.
12‑mo all‑in $2,100true monthly $175advertised $100verified · August 25, 2026
8rank
Patients who want a simple all-in monthly price with no membership and no commitment, and who may switch providers as prices move
Henry Meds charges $297 per month on a month-to-month plan, $247 per month on a 6-month plan, and $197 per month on a 12-month plan for compounded semaglutide (injection). That price includes the medication, clinical care and shipping; there is no separate membership fee. On our all-in basis, the lowest true monthly cost is $197 and the lowest 12-month total is $2,364 (12-month plan). Prices last checked August 25, 2026; status: verified.
12‑mo all‑in $2,364true monthly $197advertised $297verified · August 25, 2026
9rank
Price-focused patients comparing low-cost compounded plans
Fifty 410 charges $199 per month on a month-to-month plan for compounded semaglutide (injection). That price includes the medication, clinical care and shipping; there is no separate membership fee. On our all-in basis, the lowest true monthly cost is $199 and the lowest 12-month total is $2,388 (month-to-month plan). Because pricing rises with dose, the 12-month figure uses our 3 + 9 titration model (three months at the starting price, nine at the maintenance price). Prices last checked August 25, 2026; status: verified.
12‑mo all‑in $2,388true monthly $199advertised $199verified · August 25, 2026
10rank
Patients who already use Noom and want medication added to a behavioral program
Noom Med charges $249 per month on a 3-month plan for compounded semaglutide (injection). The first 1 month is an introductory $129 per month before the recurring price applies. That price includes the medication, clinical care and shipping; there is no separate membership fee. On our all-in basis, the lowest true monthly cost is $249 and the lowest 12-month total is $2,868 (3-month plan). Prices last checked August 25, 2026; status: verified.
12‑mo all‑in $2,868true monthly $239advertised $129verified · August 25, 2026
11rank
Price-focused patients
Zappy Health charges $249 per month on a month-to-month plan for compounded semaglutide (injection). That price includes the medication, clinical care and shipping; there is no separate membership fee. On our all-in basis, the lowest true monthly cost is $249 and the lowest 12-month total is $2,988 (month-to-month plan). Prices last checked August 25, 2026; status: verified.
12‑mo all‑in $2,988true monthly $249advertised $249verified · August 25, 2026
12rank
Patients who want a low first-month price and are prepared for a higher recurring rate
Remedy Meds charges $299 per month on a month-to-month plan for compounded semaglutide (injection). The first 1 month is an introductory $179 per month before the recurring price applies. That price includes the medication, clinical care and shipping; there is no separate membership fee. On our all-in basis, the lowest true monthly cost is $299 and the lowest 12-month total is $3,468 (month-to-month plan). Prices last checked August 25, 2026; status: verified.
12‑mo all‑in $3,468true monthly $289advertised $179verified · August 25, 2026
13rank
Patients outside the five excluded states comparing mid-market prices
Sprout Health charges $299 per month on a month-to-month plan for compounded semaglutide (injection). The first 1 month is an introductory $199 per month before the recurring price applies. That price includes the medication, clinical care and shipping; there is no separate membership fee. On our all-in basis, the lowest true monthly cost is $299 and the lowest 12-month total is $3,488 (month-to-month plan). Prices last checked August 25, 2026; status: reported.
12‑mo all‑in $3,488true monthly $290.67advertised $199reported · August 25, 2026
These providers offer semaglutide but we have not yet verified their current price against their own site. They are listed so the candidate universe is complete; they are not ranked.