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Head-to-head · computed from the pricing database · August 25, 2026

Orderly Meds vs Fifty 410

Side-by-side comparison of Orderly Meds and Fifty 410 for compounded tirzepatide and semaglutide: advertised price vs true monthly cost, 12-month totals, membership, cancellation terms, medications offered and who each is best for.

The short version

  • For compounded tirzepatide, Fifty 410's lowest 12-month all-in total is $2,046 versus $3,288 at Orderly Meds, a difference of $1,242 over a year. Month-to-month at a maintenance dose, Orderly Meds costs $299 and Fifty 410 costs $299.
  • For compounded semaglutide, Orderly Meds's lowest 12-month all-in total is $1,788 versus $2,388 at Fifty 410, a difference of $600 over a year. Month-to-month at a maintenance dose, Orderly Meds costs $149 and Fifty 410 costs $199.
  • Orderly is an all-in compounded provider whose current rates we are re-verifying.
  • Fifty 410 competes on price; we rank it once its current rates are verified.

Head-to-head answers

  • Which is cheaper over a year? Fifty 410 ($2,046 vs $3,288, $1,242 less) on 12-month all-in totals (verified / reported).
  • Which is cheaper month-to-month at maintenance doses? Fifty 410 ($299 vs $299).
  • Which has no membership fee? Orderly Meds: none. Fifty 410: none.
  • Which uses which pharmacy? Orderly Meds: PerfectRx / PerfectionRx, ProRx, Casa, Pharmacy Hub, SmartPharmaRx. Fifty 410: ProRx, BPI / The Pharmacy Hub.
  • Which is better at the maintenance dose? Orderly Meds: same price at every dose. Fifty 410: price rises with dose.
  • Which requires a video visit? Orderly Meds: asynchronous. Fifty 410: not captured.
  • Which accepts insurance? Orderly Meds: cash-pay. Fifty 410: cash-pay.
  • Which has better cancellation terms? Orderly Meds: Cancel anytime. Fifty 410: Cancel anytime.
  • Which is better for switching at an established dose? Orderly Meds: flat pricing and a month-to-month plan mean the current dose is neither penalized nor locked in.
vs

Side by side

Provider
Orderly Meds
Fifty 410
Pricing model
flat rate
flat rate
Tirzepatide, lowest 12‑mo all‑in
$3,288 ($274/mo, verified)
$2,046 ($170.50/mo, reported)
Semaglutide, lowest 12‑mo all‑in
$1,788 ($149/mo, verified)
$2,388 ($199/mo, verified)
Month-to-month true cost (maintenance)
$299/mo (tirzepatide)
$299/mo (tirzepatide)
Membership fee
None
None
Dose-based increases
Flat at every dose
Rises with dose
Price lock
No
No
Shipping
included
included
Consultation
included
included
Commitment
month-to-month; prepay discounts offered
month-to-month; prepay discounts offered
Cancellation
Cancel anytime
Cancel anytime
Brand-name medication
No
No
Insurance support
No
No
Oral / sublingual forms
Yes
No
Audience
all
all
Clinical model
Licensed provider consultation, ongoing messaging, monthly shipments
Provider consultation and messaging; monthly shipments
Value score
72/100
73/100

Green cells mark the better value on that row when both figures are known. * provisional score: pricing not yet directly verified.

Pricing in words

Orderly Meds charges $299 per month on a month-to-month plan for compounded tirzepatide (injection). The first 2 months are an introductory $149 per month before the recurring price applies. That price includes the medication, clinical care and shipping; there is no separate membership fee. On our all-in basis, the lowest true monthly cost is $299 and the lowest 12-month total is $3,288 (month-to-month plan). Prices last checked August 25, 2026; status: verified.

Fifty 410 charges $299 per month on a month-to-month plan, and $166 per month at the starting dose, rising to $183 per month at higher doses for compounded tirzepatide (injection). The first 3 months are an introductory $133 per month before the recurring price applies. That price includes the medication, clinical care and shipping; there is no separate membership fee. On our all-in basis, the lowest true monthly cost is $166 and the lowest 12-month total is $2,046 (3-month plan). Because pricing rises with dose, the 12-month figure uses our 3 + 9 titration model (three months at the starting price, nine at the maintenance price). Prices last checked August 25, 2026; status: verified.

Orderly Meds charges $149 per month on a month-to-month plan for compounded semaglutide (injection). That price includes the medication, clinical care and shipping; there is no separate membership fee. On our all-in basis, the lowest true monthly cost is $149 and the lowest 12-month total is $1,788 (month-to-month plan). Prices last checked August 25, 2026; status: verified.

Fifty 410 charges $199 per month on a month-to-month plan for compounded semaglutide (injection). That price includes the medication, clinical care and shipping; there is no separate membership fee. On our all-in basis, the lowest true monthly cost is $199 and the lowest 12-month total is $2,388 (month-to-month plan). Because pricing rises with dose, the 12-month figure uses our 3 + 9 titration model (three months at the starting price, nine at the maintenance price). Prices last checked August 25, 2026; status: verified.

Choose Orderly Meds if

Patients comparing all-in compounded plans who want oral and injectable options from one provider.

  • Offers both compounded semaglutide and tirzepatide, including oral forms
  • All-in pricing without a separate membership
  • Prepay discounts available

Choose Fifty 410 if

Price-focused patients comparing low-cost compounded plans.

  • Packages include consultation, support and free overnight or two-day shipping
  • Pricing by total milligrams is unusually transparent about what a package actually covers at each dose

What to weigh against each

Orderly Meds: Pricing pending verification and has changed since the shortages ended. Pharmacy partners and state coverage not yet verified.

Fifty 410: Effective monthly cost rises with dose: $133 (starter) to $166 (10 mg) to $183 (15 mg) per month equivalent. Three-month packages must be matched to the dose; a 144 mg package does not cover 12.5 mg weekly for twelve weeks.

How to read this comparison

Both providers were scored with the same rubric and the same cost model. Rankings never use the advertised monthly price on its own, because a low first-month number can hide a membership fee or a dose-based increase. Where a provider's price has not been directly checked against its own site, we say so and do not rank it on cost. Compounded tirzepatide and semaglutide are not FDA-approved; the only FDA-approved products are Zepbound, Mounjaro, Wegovy, Ozempic and Rybelsus. See the methodology and important safety information.

Frequently asked questions

Is Orderly Meds cheaper than Fifty 410?

For compounded tirzepatide, Fifty 410's lowest 12-month all-in total is $2,046 versus $3,288 at Orderly Meds, a difference of $1,242 over a year. Month-to-month at a maintenance dose, Orderly Meds costs $299 and Fifty 410 costs $299.

Does Orderly Meds or Fifty 410 charge a membership fee?

Orderly Meds: no separate membership fee. Fifty 410: no separate membership fee.

Which is better for tirzepatide, Orderly Meds or Fifty 410?

Orderly Meds offers tirzepatide; Fifty 410 offers tirzepatide. Orderly is an all-in compounded provider whose current rates we are re-verifying. Fifty 410 competes on price; we rank it once its current rates are verified.

Editor's pick · best overall

Editor's pick: NexLife value score 92/100

How the pick is chosen: the highest value score in our database (cost, transparency, flexibility, care and verification) as of August 25, 2026; it changes automatically when the data does. NexLife also pays for a labeled sponsored placement on this site, which does not enter the score. How the score works · Advertising disclosure.

What every plan includes

  • Same price at every dose. No hidden fees.
  • Free expedited shipping.
  • No membership fees.
  • Doctor-led plans, coaching and an active community.

Prices verified, checked August 25, 2026.

Included at no extra cost

  • Provider review and ongoing medical guidance$199Included
  • Personalized nutrition plan (GLP-1 focused)$99Included
  • 1:1 fitness call with a certified wellness coach$79Included

Stated values are NexLife's own figures, not market prices.

Plan pages

Regular protocol Standard injectable plans; the ones our rankings use
Microdose protocol Lower-dose plans; listed in our database, not ranked
Sublingual (ODT) protocol Orally disintegrating tablets; listed, not ranked

Read the full review and the cons →